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KMID : 1188320150090040470
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Gut and Liver
2015 Volume.9 No. 4 p.470 ~ p.477
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Endoscopic and Oncologic Outcomes of Endoscopic Resection for Superficial Esophageal Neoplasm
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Kim Do-Hoon
Jung Hwoon-Yong
Gong Eun-Jeong
Choi Ji-Young
Ahn Ji-Yong
Kim Mi-Young
Choi Kwi-Sook
Lee Jeong-Hoon
Choi Kee-Don
Song Ho-June
Lee Gin-Hyug
Kim Jin-Ho
Park Young-Soo
Baek Seung-Hee
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Abstract
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Background/Aims:Endoscopic resection (ER) of superficial esophageal neoplasm (SEN) is a technically difficult procedure. We investigated the clinical outcomes of ER for SEN to determine its feasibility and effectiveness.
Methods:Subjects who underwent ER for SEN at Asan Medical Center between December 1996 and December 2010 were eligible. The clinical features of patients and tumors, histopathological characteristics, adverse events, ER results and survival were investigated.
Results:A total of 129 patients underwent ER for 147 SENs. En bloc resection (EnR) was performed in 118 lesions (80.3%). Complete resection (CR) was accomplished in 128 lesions (86.5%), and curative resection (CuR) was performed in 118 lesions (79.7%). The EnR, CR, and CuR rates were significantly greater in the endoscopic submucosal dissection group when compared to those in the endoscopic resection group. Adverse events occurred in 22 patients (17.1%), including bleeding (n=2, 1.6%), perforation (n=12, 9.3%), and stricture (n=8, 6.2%). Local tumor recurrence occurred in 2.0% of patients during a median follow-up of 34.8 months. The 5-year overall and disease-specific survival rates were 94.0% and 97.5%, respectively.
Conclusions:ER is a feasible and effective method for the treatment of SEN as indicated by favorable clinical outcomes.
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KEYWORD
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Esophageal neoplasms, Treatment outcome, Endoscopic resection
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